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The Precautionary and Prohibited Medications Database

Maintained by a collaboration of the University at Buffalo Pharmacology Specialty Laboratory and Frontier Science & Technology Research Foundation

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Medication Information

Display Name Lopinavir/​Ritonavir
Medication Class ARV
Abbreviations LPV/r
Alternative Names
Chemical Name
Brand Names Kaletra
Components Lopinavir, Ritonavir
Generic Names
Number of prohibited interactions 6
Number of precautionary interactions 29
Number of unknown or no interactions 9
Total number of interactions 44

Medications that interact with Lopinavir/​Ritonavir

Interacting Medication Designation Last Updated
Bedaquiline Precautionary 17-Jul-2018 View Details
Boceprevir Prohibited 16-Jul-2018 View Details
Buprenorphine/Naloxone Precautionary View Details
Carbamazepine Precautionary 30-Jul-2018 View Details
Colchicine Precautionary 14-Aug-2018 View Details
Cyclosporine Precautionary 26-Jun-2018 View Details
Daclatasvir Precautionary 18-Jul-2018 View Details
Dasabuvir/Ombitasvir/Paritaprevir/Ritonavir Prohibited View Details
Dolutegravir Unknown or no reaction 13-Jul-2018 View Details
Esomeprazole Precautionary View Details
Etonogestrel Unknown or no reaction 20-Jul-2018 View Details
Etoposide Precautionary 14-Aug-2018 View Details
Famotidine Unknown or no reaction 14-Aug-2018 View Details
Fenofibric Acid Unknown or no reaction View Details
Garlic Precautionary 02-Jul-2018 View Details
Gemfibrozil Precautionary View Details
Ginseng Unknown or no reaction View Details
Glecaprevir/Pibrentasvir Prohibited 01-Mar-2022 View Details
Grazoprevir (Single Agent) Prohibited 16-Jul-2018 View Details
Hypoxis Precautionary View Details
Ifosfamide Precautionary 27-Jun-2018 View Details
Irinotecan Precautionary View Details
Lamotrigine Precautionary 01-Aug-2018 View Details
Maraviroc Precautionary 20-Jul-2018 View Details
Medroxyprogesterone Precautionary View Details
Methadone Precautionary 30-Jul-2018 View Details
Midazolam Precautionary 26-Jun-2018 View Details
Nizatidine Unknown or no reaction 26-Jun-2018 View Details
Phenobarbital Prohibited 30-Jul-2018 View Details
Phenytoin Prohibited 30-Jul-2018 View Details
Pitavastatin Unknown or no reaction View Details
Prednisone Precautionary 27-Jun-2018 View Details
Pretomanid Precautionary View Details
Rabeprazole Precautionary View Details
Ranitidine Unknown or no reaction 26-Jun-2018 View Details
Rifabutin Precautionary 05-Sep-2018 View Details
Rifampin Precautionary 02-Jul-2018 View Details
Sofosbuvir/Velpatasvir Unknown or no reaction 18-Jul-2018 View Details
Sutherlandia Precautionary View Details
Tacrolimus Precautionary 03-Aug-2018 View Details
Telaprevir Precautionary 10-Jul-2018 View Details
Tenofovir Alafenamide Precautionary 03-Aug-2018 View Details
Valproic Acid Precautionary 01-Aug-2018 View Details
Voriconazole Precautionary 03-Jul-2018 View Details