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The Precautionary and Prohibited Medications Database

Maintained by a collaboration of the University at Buffalo Pharmacology Specialty Laboratory and Frontier Science & Technology Research Foundation

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Medication Information

Display Name Simeprevir
Medication Class Anti-HCV
Abbreviations
Alternative Names
Chemical Name TMC435
Brand Names Olysio
Components
Generic Names
Number of prohibited interactions 4
Number of precautionary interactions 9
Number of unknown or no interactions 13
Total number of interactions 26

Medications that interact with Simeprevir

Interacting Medication Designation Last Updated
Atorvastatin Precautionary 18-Jul-2018 View Details
Caffeine Unknown or no reaction 18-Jul-2018 View Details
Cyclosporine Precautionary 18-Jul-2018 View Details
Daclatasvir Precautionary View Details
Darunavir/Ritonavir Prohibited 18-Jul-2018 View Details
Dextromethorphan Unknown or no reaction 18-Jul-2018 View Details
Digoxin Precautionary 18-Jul-2018 View Details
Dolutegravir Unknown or no reaction 24-Jul-2018 View Details
Efavirenz Prohibited View Details
Erythromycin Prohibited 18-Jul-2018 View Details
Escitalopram Unknown or no reaction 18-Jul-2018 View Details
Ethinylestradiol/Norethindrone Unknown or no reaction 18-Jul-2018 View Details
Ledipasvir/Sofosbuvir Unknown or no reaction 20-Jul-2018 View Details
Methadone Unknown or no reaction 18-Jul-2018 View Details
Omeprazole Unknown or no reaction 18-Jul-2018 View Details
Raltegravir Unknown or no reaction 18-Jul-2018 View Details
Rifampin Prohibited 18-Jul-2018 View Details
Rilpivirine Unknown or no reaction 18-Jul-2018 View Details
Ritonavir (as stand alone agent) Precautionary 18-Jul-2018 View Details
Rosuvastatin Precautionary 18-Jul-2018 View Details
Simvastatin Precautionary 18-Jul-2018 View Details
Sofosbuvir Unknown or no reaction 18-Jul-2018 View Details
TMC647055 Precautionary View Details
Tacrolimus Precautionary 18-Jul-2018 View Details
Tenofovir Disoproxil Fumarate Unknown or no reaction 18-Jul-2018 View Details
Warfarin Unknown or no reaction 18-Jul-2018 View Details